Stoke Therapeutics

Answer: Stoke Therapeutics's phone number is 78********

Answer: Stoke Therapeutics's official website is https://stoketherapeutics.com

Answer: Stoke Therapeutics's revenue is $1 Million to $5 Million

Answer: Stoke Therapeutics's SIC: 2834

Answer: Stoke Therapeutics's NAICS: 561110

Answer: Stoke Therapeutics has 51-200 employees

Answer: Stoke Therapeutics is in Biotechnology

Answer: Stoke Therapeutics contact info: Phone number: 78******** Website: https://stoketherapeutics.com

Answer: Stoke Therapeutics (Nasdaq: STOK), is a biotechnology company dedicated to addressing the underlying cause of severe diseases. The company is pursuing an entirely new approach to treating severe diseases. We are initially focused on diseases of the central nervous system and the eye, with an emphasis on haploinsufficiencies, which are diseases caused by a loss of about half of the normal protein function. Rather than replace, repair or edit faulty genes, we aim to increase or stoke protein output from healthy genes to restore functional protein levels using our proprietary TANGO (Targeted Augmentation of Nuclear Gene Output) platform. In all, Stoke has identified ~6500 genes with a TANGO signature, representing broad potential for our approach to help people with severe diseases. The early results have been promising. Stokes first medicine in development, STK-001 has demonstrated positive Phase 1/2 results for the treatment of Dravet syndrome, a severe and progressive genetic epilepsy that is associated with a number of debilitating non-seizure comorbidities. Behind that, is STK-002, a potential treatment for autosomal dominant optic atrophy (ADOA), the most common inherited optic nerve disorder. Clinical studies of STK-002 are anticipated to start in 2024. The company is pursuing potential treatments for three additional neurodevelopmental disorders, including Syngap1 and Rett syndrome, in collaboration with Acadia Pharmaceuticals. Stoke is headquartered in Bedford, Massachusetts with offices in Cambridge, Massachusetts.

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