Genprex
Biotechnology, 1601 Trinity St, Austin, Texas, 78712, United States, 11-50 Employees
Phone Number: 51********
Who is GENPREX
Genprex, Inc. is a clinical-stage gene therapy company focused on developing life-changing therapies for patients with cancer and diabetes. Genprexs technologies are designed to administe...
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- Headquarters: 1601 Trinity St, Austin, Texas, 78712, United States
- Date Founded: 2009
- Employees: 11-50
- Revenue: $25 Million to $50 Million
- Active Tech Stack: See technologies
- CEO: Michael Redman
Industry: Biotechnology
SIC Code: 2834 | NAICS Code: 325412 | Show More
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Frequently Asked Questions Regarding Genprex
Answer: Genprex's headquarters are located at 1601 Trinity St, Austin, Texas, 78712, United States
Answer: Genprex's phone number is 51********
Answer: Genprex's official website is https://genprex.com
Answer: Genprex's revenue is $25 Million to $50 Million
Answer: Genprex's SIC: 2834
Answer: Genprex's NAICS: 325412
Answer: Genprex has 11-50 employees
Answer: Genprex is in Biotechnology
Answer: Genprex contact info: Phone number: 51******** Website: https://genprex.com
Answer: Genprex, Inc. is a clinical-stage gene therapy company focused on developing life-changing therapies for patients with cancer and diabetes. Genprexs technologies are designed to administer disease-fighting genes to provide new therapies for large patient populations with cancer and diabetes who currently have limited treatment options. Genprex works with world-class institutions and collaborators to develop drug candidates to further its pipeline of gene therapies in order to provide novel treatment approaches. Genprexs oncology program utilizes its proprietary, non-viral ONCOPREX Nanoparticle Delivery System, which the Company believes is the first systemic gene therapy delivery platform used for cancer in humans. ONCOPREX encapsulates the gene-expressing plasmids using lipid nanoparticles. The resultant product is administered intravenously, where it is then taken up by tumor cells that express tumor suppressor proteins that are deficient in the body. The Companys lead product candidate, REQORSA (quaratusugene ozeplasmid), is being evaluated in three clinical trials as a treatment for non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). Both NSCLC clinical programs received a Fast Track Designation from the Food and Drug Administration. Genprexs diabetes gene therapy approach is comprised of a novel infusion process that uses an endoscope and an adeno-associated virus (AAV) vector to deliver Pdx1 and MafA genes directly to the pancreas. In models of Type 1 diabetes, GPX-002 transforms alpha cells in the pancreas into functional beta-like cells, which can produce insulin but are distinct enough from beta cells to evade the bodys immune system. In a similar approach, GPX-003 for Type 2 diabetes, where autoimmunity is not at play, is believed to rejuvenate and replenish exhausted beta cells.
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