Applied Molecular Transport

Answer: Applied Molecular Transport's phone number is 65********

Answer: Applied Molecular Transport's official website is https://appliedmt.com

Answer: Applied Molecular Transport's revenue is $10 Million to $25 Million

Answer: Applied Molecular Transport's SIC: 2834

Answer: Applied Molecular Transport's NAICS: 325412

Answer: Applied Molecular Transport has 51-200 employees

Answer: Applied Molecular Transport is in Biotechnology

Answer: Applied Molecular Transport contact info: Phone number: 65******** Website: https://appliedmt.com

Answer: Applied Molecular Therapeutics (AMT), a public biopharmaceutical company based in South San Francisco, California, is committed to developing novel, oral biological therapeutics to treat severe autoimmune, metabolic and inflammatory diseases. AMT is leveraging its propriety technology platforms to create gastrointestinal (GI)-select therapeutics that harness naturally occurring transport and targeting mechanisms to cross the protective barrier of the intestinal epithelium (IE). Once across the IE, the therapeutics gain privileged access to the immune cell-rich environment of the GI tissue as well as the hepatic portal system and downstream systemic circulation. With this privileged access, AMTs goal is to develop transformative new oral therapeutic treatment options that offer patients greater efficacy and tolerability than available with todays therapeutics. AMT has a robust pipeline of oral biologic product opportunities, including AMT-101 which is currently in Phase 1b clinical development for the treatment of adults with ulcerative colitis (UC). AMT-101 is a novel, gut-selective, investigational oral biologic fusion protein of interleukin 10 (IL-10), an anti-inflammatory cytokine. Derived from AMTs proprietary platforms, AMT-101 is engineered to cross the selective barrier of the IE and enhance localized IL-10 directly within the immune-cell rich environment of GI tissue where up to 75 percent of immune cells reside. This direct targeting of the immune system creates the potential for AMT-101 to address, at its point of origin, the immune dysregulation that gives rise to UC and other inflammatory bowel diseases, and restore immune homeostasis with minimal systemic exposure and potentially fewer adverse events compared to systemic administration of IL-10. AMT has amassed a broad global IP portfolio surrounding its multiple technology platforms and therapeutic programs.

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