Acelot

Acelot

Biotechnology, 5385 Hollister Ave Ste 111, Palo Alto, California, 93111, United States, 1-10 Employees

acelot.com

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Who is ACELOT

Acelot is treating functional protein misfolding diseases where the appropriate therapeutic mechanism is a restoration of the normal protein homeostasis. Functional misfolded proteins are...

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  • 5385 Hollister Ave Ste 111, Palo Alto, California, 93111, United States Headquarters: 5385 Hollister Ave Ste 111, Palo Alto, California, 93111, United States
  • 2006 Date Founded: 2006
  • 1-10 Employees: 1-10
  • dollar-icon Revenue: $5 Million to $10 Million
  • tech-icon Active Tech Stack: See technologies

industries-icon Industry: Biotechnology

SIC SIC Code: 1799 | NAICS Code: 238990 | Show More

checked-icon Does something look wrong? Fix it. | View contact records from ACELOT

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Frequently Asked Questions Regarding Acelot

Answer: Acelot's headquarters are located at 5385 Hollister Ave Ste 111, Palo Alto, California, 93111, United States

Answer: Acelot's official website is https://acelot.com

Answer: Acelot's revenue is $5 Million to $10 Million

Answer: Acelot's SIC: 1799

Answer: Acelot's NAICS: 238990

Answer: Acelot has 1-10 employees

Answer: Acelot is in Biotechnology

Answer: Acelot top competitors include: Mantra Bio , Maze Therapeutics

Answer: Acelot contact info: Phone number: Website: https://acelot.com

Answer: Acelot is treating functional protein misfolding diseases where the appropriate therapeutic mechanism is a restoration of the normal protein homeostasis. Functional misfolded proteins are found in various diseases such as ALS, FTD, Parkinsons, diabetes and cancer. Acelots platform combines generative AI, molecular dynamics simulations and proprietary assays to discover small molecules that restore the homeostasis of misfolded proteins in various diseases. We have a pipeline of hit-to-lead discovery compounds across multiple indications, along with an IND-ready candidate for ALS. Our platform was invented by UCSB Computer Science Professor Dr. Ambuj Singh. Acelots first development candidate, ACE-2223, is a first-in-class orally bioavailable small molecule that will undergo IND-enabling studies in 2024. ACE-2223 disrupts the misfolded forms of TDP43 and restores functional TDP43. It acts upon the misfolded conformations of TDP43 found across various patient populations, including ALS, FTD and Alzheimers. ACE-2223 has excellent brain penetrance and ADME properties. Acelot also has a robust discovery pipeline.

Answer:

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