Ablative Solutions
Medical Devices, 250 E 5th St, Wakefield, Massachusetts, 45202, United States, 11-50 Employees
Phone Number: 16*********
Who is ABLATIVE SOLUTIONS
Ablative Solutions is a clinical-stage medical device start-up that is pioneering the novel approach of Transcatheter Perivascular Alcohol Denervation for the treatment of hypertension. H...
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Headquarters: 250 E 5th St, Wakefield, Massachusetts, 45202, United States
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Date Founded: 2011
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Employees: 11-50
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Revenue: $1 Billion and Over
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Active Tech Stack: See technologies
Industry: Medical Devices
SIC Code: 2834
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NAICS Code: 621111 |
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Frequently Asked Questions Regarding Ablative Solutions
Answer: Ablative Solutions's headquarters are located at 250 E 5th St, Wakefield, Massachusetts, 45202, United States
Answer: Ablative Solutions's phone number is 16*********
Answer: Ablative Solutions's official website is https://ablativesolutions.com
Answer: Ablative Solutions's revenue is $1 Billion and Over
Answer: Ablative Solutions's SIC: 2834
Answer: Ablative Solutions's NAICS: 621111
Answer: Ablative Solutions has 11-50 employees
Answer: Ablative Solutions is in Medical Devices
Answer: Ablative Solutions contact info: Phone number: 16********* Website: https://ablativesolutions.com
Answer: Ablative Solutions is a clinical-stage medical device start-up that is pioneering the novel approach of Transcatheter Perivascular Alcohol Denervation for the treatment of hypertension. Hypertension, or high blood pressure, is a modern day epidemic, affecting more than one billion people worldwide and an estimated 67 million in the United States alone. Often described as "the silent killer", hypertension is strongly associated with heart disease and stroke. Increased sympathetic nerve activity plays a key role in the pathophysiology of hypertension. By disrupting, or "denervating" these sympathetic nerves, clinicians can alter this overactive signaling process and reduce patients' blood pressure. First-generation approaches using radio-frequency energy produced encouraging results, but these systems are challenged by their inability to reach the target nerves, which lie outside of the treatment range of the energy employed. Ablative Solutions has developed the Peregrine System to perform chemical renal denervation, using alcohol as the neurolytic agent, which may have substantial advantages over energy-based systems. The Peregrine System Infusion Catheter features three equally spaced micro-needles that enable the controlled infusion of a neurolytic agent directly into the perivascular space around the renal arteries, where the sympathetic nerves reside. The Peregrine System has received FDA 510(k) clearance for the infusion of diagnostic and therapeutic agent into the perivascular area of the peripheral vasculature. The device has also received the CE Certificate of Conformity in Europe for the treatment of hypertensive patients. Ablative Solutions is currently conducting a post-market clinical study in Europe to secure additional clinical data. The company is also in the planning stage of a randomized clinical trial in the United States to seek approval for the system's use in the treatment of hypertension.
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